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SUMMARY:Decoding the Physical Code of Living Matter via Dynamic Force Spec
 troscopy
DTSTART:20260415T053000Z
DTEND:20260415T073000Z
DTSTAMP:20260424T021800Z
UID:indico-event-195@indico.phys.nthu.edu.tw
CONTACT:kuoan@phys.nthu.edu.tw
DESCRIPTION:Speakers: Ching-Hwa Kiang (Department of Physics & Astronomy\,
  Rice University)\n\nMeasuring the physical properties of complex\, out-of
 -equilibrium biological systems requires precise nanoscale investigation. 
 At this scale\, living matter is governed by rugged energy landscapes that
  dictate both form and function. Recent advancements in single-molecule an
 d single-cell dynamic force spectroscopy provide a powerful means to decod
 e this underlying mechanical language. Utilizing atomic force microscopy (
 AFM)\, we developed a novel\, label-free method to characterize both biomo
 lecular dynamics and cellular states through their unique mechanical and a
 coustic signatures. By analyzing the force responses of diverse systems\, 
 including DNA\, multimeric proteins\, graphene nanoribbons\, and mammalian
  cells\, the thermodynamics of living matter can be directly observed in a
 ction. Ultimately\, establishing these nanoscale mechanical signatures pro
 vides a crucial framework for addressing complex scientific and medical ch
 allenges\, such as protein folding mechanics and advanced cancer diagnosis
 .\n\nhttps://indico.phys.nthu.edu.tw/event/195/
LOCATION:L124\, Physics Building (NTHU)
URL:https://indico.phys.nthu.edu.tw/event/195/
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