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SUMMARY:Route selection\, geometry\, and delayed exit in active condensate
  size control
DTSTART:20260513T053000Z
DTEND:20260513T073000Z
DTSTAMP:20260514T122100Z
UID:indico-event-203@indico.phys.nthu.edu.tw
CONTACT:kuoan.wu@gmail.com
DESCRIPTION:Speakers: Min-Jhe Lu (Institute of Computational and Modeling 
 Science\, NTHU)\n\nBiomolecular condensates are active soft-matter systems
  whose size and dissolution are regulated by biochemical reactions. A cent
 ral question is how chemical activity generates an effective mechanical fo
 rce on a slow collective coordinate\, such as condensate radius.\nIn this 
 talk\, I will discuss a reduced description in which reaction currents are
  projected onto a slow radius mode\, leading to an effective radius-force 
 balance for condensate growth and shrinkage. In a fast-mixing limit\, the 
 dynamics reduce to a competition between assembly and turnover opposed by 
 a geometric restoring load. Their balance determines the condensate size\,
  while the local branch structure controls mechanical softening and delaye
 d loss of stability under slow driving.\nI will further discuss how this r
 educed picture emerges from reaction–diffusion and phase-field models\, 
 and where it breaks down due to transport gradients\, heterogeneous activi
 ty\, and fluctuations. The framework separates biochemical driving\, geome
 tric resistance\, kinetic timescales\, and noise as distinct layers of act
 ive condensate dynamics.\n\nhttps://indico.phys.nthu.edu.tw/event/203/
LOCATION:L124\, Physics Building (NTHU)
URL:https://indico.phys.nthu.edu.tw/event/203/
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